To compare the effectiveness of Chlorhexidine and Povidine iodine in preventing surgical site infections (SSIs) in C-section deliveries


  • Habiba Sharaf Ali Professor Obstetric &Gynecology Ziauddin University Karachi
  • Shaheena Ishtiaq Consultant gynecologist Ziauddin Hospital Clifton Campus
  • Summiya Yayia Postgraduate student Ziauddin University Karachi


Surgical site infections, skin preparation


Background: Surgical site infections (SSIs) are a significant concern in healthcare settings,

leading to increased morbidity, mortality, and financial burden. Effective skin preparation

 using suitable antiseptic agents is crucial for preventing SSIs.

Objective: This study aimed to compare the effectiveness of Chlorhexidine and Povidine iodine in preventing SSIs in C-section deliveries.


Methods: The study was conducted at a medical university and hospital in Karachi, Pakistan, over a six-month period. A sample size of 35 participants was calculated, and a non-probability consecutive sampling technique was used to select participants. Two groups were randomly assigned, with Group 1 receiving Chlorhexidine gluconate and Group 2 receiving Povidone-Iodine for skin preparation. Data on various factors were recorded, and the occurrence of SSIs within ten days of cesarean delivery was assessed.

Results: The study included women aged 18 to 45 years. The efficacy of Chlorhexidine and Povidine iodine in preventing SSIs was evaluated. The results showed that Chlorhexidine was effective in preventing SSIs in 94.3% of cases, while Povidine iodine was effective in 91.4% of cases. However, no significant difference was observed between the two groups.The study results were consistent with previous research showing a reduction in SSI rates with the use of Chlorhexidine or Povidine iodine. However, other studies have reported conflicting

findings. The overall rate of SSI was lower in the Chlorhexidine group, but contextual factors and adherence to infection control practices may influence outcomes..

Conclusion: This study contributes to the existing body of knowledge on preventing SSIs in C-section deliveries. While Chlorhexidine and Povidine iodine showed comparable efficacy, Chlorhexidine appeared to be slightly more effective in reducing SSIs. However, the limitations of the study and the need for further research in different healthcare settings should be considered.





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