Changing trends of pyogenic microorganisms in a tertiary care hospital

  • Nazish Babar Assistant Professor Microbiology, Fazaia Medical College. Air University. Islamabad
  • Zaheer Ahmed Chaudhary Professor of Microbiology, Fazaia Medical College. Air University. Islamabad
  • Rubina Riaz Assistant Professor Histopathology, Fazaia Medical College. Air University. Islamabad
  • Hijab Shah Assistant Professor Histopathology, Fazaia Medical College. Air University. Islamabad
  • Bushra Anwar Associate Professor Hematology, Fazaia Medical College. Air University. Islamabad
  • Rabia Anjum Assistant Professor Microbiology, Benazir Bhutto Hospital Rawalpindi

Abstract

Objective: To determine the predominant microorganisms responsible for pyogenic infections and prospective monitoring of the changing trends in their antibiotic susceptibility profile.


Methodology: A cross sectional study was conducted at the Department of Microbiology, Rawal Institute of Health Sciences, Islamabad, from April 2015 to February 2016. Pus and pus swab samples were randomly collected from different body sites both from the males and females from any age group. Patients who were already taking antibiotics, those on steroids or suffering from chronic illnesses were excluded from the study. Inoculation of the samples on the respective culture media was done followed by Gram stain, biochemical reactions and antibiotic susceptibility testing carried out by Kirby Bauer disc diffusion method and its interpretation as per Clinical Laboratory and Standards Institute (CLSI) guidelines. Data was collected on preformed table and analysis was done by using SPSS version 21.


Results: 127 pus samples were analyzed, out of which 103 yielded a positive culture. Staphylococcus aureus/Methicillin resistant Staphylococcus aureus (MRSA) was the commonest organism among the Gram positive organisms which showed maximum susceptibility to vancomycin (100%) and Linezolid (92%). Among the Gram negative organisms Escherichia coli was the commonest followed by Pseudomonas aeruginosa and other organisms.


Conclusion:  The changing trends of pyogenic organisms have to be monitored prospectively to counter the global epidemic and to detect the constantly increasing burden of antibiotic resistance leading to it.

Published
2019-10-13
How to Cite
BABAR, Nazish et al. Changing trends of pyogenic microorganisms in a tertiary care hospital. Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University, [S.l.], v. 15, n. 2, p. 71-75, oct. 2019. ISSN 1815-2287. Available at: <https://www.apims.net/index.php/apims/article/view/243>. Date accessed: 13 nov. 2019.
Section
Original Articles