Frequency of Culture-Proven Sepsis in Neonates Born to Mothers with Premature Rupture of Membranes

Authors

  • Sana Ejaz PIMS/SZABMU
  • Nighat Haider Associate Professor PEADS medicine
  • Bushra Adeel Fellow in FCPS Neonatology PIMS/SZABMU , Islamabad
  • Faiza Qayyum Resident in Pediatric medicine, PIMS/SZABMU , Islamabad
  • Sara Ambreen Resident in Pediatric medicine, PIMS/SZABMU , Islamabad
  • Hifza Rehman Resident in Pediatric medicine, PIMS/SZABMU , Islamabad

DOI:

https://doi.org/10.48036/apims.v20iSUPPL-1.855

Abstract

Objectives: To determine frequency of culture proven sepsis in neonates born to mother with premature rupture of membranes (PROM).

Methodology: This observational cross-sectional study was carried out from June 2022 to December 2022 at department of neonatology PIMS Islamabad.  A total of 305 neonates fulfilling the inclusion criteria were included in the study. At the time of inclusion baseline characteristics were documented. After that blood samples of all the children with signs and symptoms of neonatal sepsis were sent for blood culture and sensitivity for diagnosis confirmation, organism identification and antibiotic sensitivity. Data was analyzed using SPSS 22:00.

Results: In our study, mean gestational age of neonates was 38.33 ± 1.84 weeks. There were 177 (58.04%) male and 128 (41.96%) female. Mean duration of PROM was 20.98 ± 1.44 hours. Frequency of culture proven sepsis in neonates born to mother with PROM was 82 (26.88%). Most common organism which was isolated in blood cultures was Klebsiella spp. 40 (48.78%).

Conclusion: Premature rupture of membranes increases the chances of neonates to acquire sepsis. Special care should be taken for such neonates in NICU for improved outcomes.

Keywords: Neonate, Organism, PROM, Drug sensitivity, Sepsis.

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Published

2024-07-19

Issue

Vol. 20 No. SUPPL-1 (2024): July-Sept

Section

Original Articles

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Copyright (c) 2024 Sana Ejaz, Associate Professor PEADS medicine, Associate Professor PEADS medicine, Dr Bushra Adeel, Dr Faiza Qayyum, Dr Sara Ambreen, Dr Hifza Rehman

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0/.) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.