Role of Elastography in Differentiating Malignant and Benign Thyroid Nodules using FNAC as a Reference Standard


  • Maham Munir Awan Associate Professor of Radiology Dept. Nishtar Medical University, Multan.
  • Malik Mudasir Hassan Associate Professor of Radiology Dept. Quaid e Azam Medical College Bahawalpur
  • Hina Hanif Mughal Associate Professor Radiology Dept. Rawalpindi Medical University. HOD Radiology Benazir Bhutto Hospital


Elastography, Thyroid nodules, Fine needle aspiration cytology (FNAC), benign


Objective: is to determine the efficacy of elastography in differentiation of malignant and benign thyroid nodules taking fine needle aspiration cytology as reference standard.

Study design: Prospective, descriptive study

Place and duration: Study was conducted at Radiology Department of Nishtar Hospital, Multan, from January 2023 December 2023.

Methodology: A total of 180 patients having one or more solid thyroid nodules diagnosed on conventional ultrasound were enrolled in study. After consent all patients were underwent strain elastography under standard protocol and findings were compared with cytological findings.

Results: The study included a total of 180 patients with an average age of 46.38±12.21 years, with males comprising 76.1% and females 23.9%. Among them, 9.4% had malignant thyroid nodules, while 90.6% had benign ones. In terms of diagnostic accuracy, 13 patients showed both positive cytology FNAC and positive ultrasound elastography (true positive), whereas 7 patients had negative cytology FNAC but positive ultrasound elastography (false positive).

Conclusion: Elastography have high efficacy to differentiate malignant thyroid nodules and benign thyroid nodules and can be used in replacement of fine needle aspiration cytology (FNAC).





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