Prevalence of Helicobacter Pylori Infection Among Patients With Psoriasis

Abstract

Objective: To determine the frequency of Helicobacter pylori infection in patients with psoriasis.

Methodology: This cross sectional descriptive study was done at Department of Dermatology, Liaquat University of Medical and Health Sciences Hospital, Jamshoro/Hyderabad, from August 2019 to February 2020. All subjects with psoriasis were further evaluated for the Helicobacter pylori infection by taking 2cc venous blood sample and sent to the laboratory for analysis. The Helicobacter pylori infection was labeled as positive and negative according to the cut off values. Descriptive statistics were calculated. Stratification was done and post stratification Chi Square test was applied. P-value ?0.05 was taken as significant.

Results: There were 58.2% male and 41.8% female patients. Mean age was 48.17±7.28 years. Mean disease duration was 4.44±1.90 years. it was observed that 64.6% patients were from urban and 35.4% were from rural areas. Helicobacter pylori infection was observed in 68.4% patients. Results showed significant association of helicobacter pylori infection with iron deficiency anemia.

Conclusion: The study found a high frequency of Helicobacter pylori infection (68.4%) among patients with psoriasis, suggesting a possible association between the infection among males, younger individuals, hypertensive patients, and urban residents.

Keywords: Helicobacter pylori, infection, psoriasis